Kurtosis analysis of neural diffusion organization
نویسندگان
چکیده
منابع مشابه
Kurtosis analysis of neural diffusion organization
A computational framework is presented for relating the kurtosis tensor for water diffusion in brain to tissue models of brain microstructure. The tissue models are assumed to be comprised of non-exchanging compartments that may be associated with various microstructural spaces separated by cell membranes. Within each compartment the water diffusion is regarded as Gaussian, although the diffusi...
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E. S. Hui, S. H. Fung, and E. X. Wu Laboratory of Biomedical Imaging and Signal Processing, The University of Hong Kong, Hong Kong, Hong Kong, Department of Radiology Research, The Methodist Hospital Research Institute, Houston, Texas, United States, Department of Radiology, Weill Medical College of Cornell University, New York, New York, United States, Department of Electrical & Electronic Eng...
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MR diffusion kurtosis imaging (DKI) was proposed recently to study the deviation of water diffusion from Gaussian distribution. Mean kurtosis, the directionally averaged kurtosis, has been shown to be useful in assessing pathophysiological changes, thus yielding another dimension of information to characterize water diffusion in biological tissues. In this study, orthogonal transformation of th...
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Introduction: Diffusion weighted imaging (DWI) and the calculated apparent diffusion coefficient (ADC) is showing potential for improving detection of prostate cancer (PCa), as the increased cellularity of many tumors is associated with restricted water diffusion and thus with a decreased ADC [1,2]. The ADC assumes Gaussian water diffusion and is calculated by monoexponential fitting. However, ...
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Purpose To evaluate the clinical utility of diffusion kurtosis tensor imaging in the characterization of cerebral glioma and investigate correlations between diffusion and kurtosis metrics with tumor cellularity. Materials and Methods A group of 163 patients (age: 40.5 ± 11.5 years) diagnosed with cerebral glioma underwent diffusion kurtosis tensor imaging with a 3 T scanner. Diffusion and kurt...
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ژورنال
عنوان ژورنال: NeuroImage
سال: 2015
ISSN: 1053-8119
DOI: 10.1016/j.neuroimage.2014.11.015